Search results for " fiber-based"
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Dynamic Binding Capacity in Fiber-Based Chromatography
Fiber-based matrices for affinity purification is suitable for rapid-cycling chromatography. Fiber chromatography matrices such as Fibro PrismA can bind a large amount of protein in a frac…
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Speeding Up mAb Purification Using Fiber-based Technology
Learn how to automate high throughput monoclonal antibody (mAb) purification and improve throughput significantly using fiber-based chromatography.
With purification cycles in minutes rather th…
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Fiber-Based Protein A Chromatography for HTPD
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified proteins, and often substantial hands-on time is required fo…
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Cytiva Opens Biotechnology Manufacturing Center in UK
In the first half of 2019, the center will start producing a fiber-based chromatography purification platform, which has the potential to improve efficiency in the purification steps of manufacturing …
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Enhancing Resins Addresses Purification Concerns
Ihre suggests that for such target molecules, a more open pore structure, such as that seen in fiber-based devices, may allow for high binding capacities and productivity gains. “In studies of plasmid…
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Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification
Bayer worked with Cytiva to evaluate a fiber-based alternative, Fibro PrismA, to determine its potential as a truly single-use mAb capture technology. The team assessed scalability from lab- to proces…
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Cytiva Advances Fiber Chromatography Technology with New Launch
The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.
On Jan. 27, 2021, Cyti…
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Scaling Up Novel Therapies
For example, a new collaboration (1) that involves Cytiva, Cobra Biologics, and UK’s Center for Process Innovation, is working on new ways to use fiber-based chromatography to improve AAV scale-up. Ot…
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Innovative Chromatography Resins Can Improve Purity and Quality
Meanwhile, an innovation such as a fiber-based protein A chromatography resin offers advantages over traditional resins. “Until recently, chromatography based on different porous bead formats has been…
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Start-to-Finish Connected Manufacturing
That’s why we are demonstrating our mAb process that tested the performance of a new Xcellerex automatic perfusion system (APS) bioreactor, compared resin and fiber-based chromatography, and utilized …